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Sesame (Sesamum indicum)



Depletions

Sesame/Nutrient Depletion:
  • CalciumCalcium: Based on clinical evidence, calcium from sesame seeds did not cause an acute response in calcium metabolism (572).
  • CholesterolCholesterol: In clinical trials, sesame decreased total cholesterol, LDL cholesterol, triglycerides, and apoprotein B, with elevated HDL cholesterol levels under some conditions (20; 25; 26; 23; 83; 306; 36), but not others (21; 497; 15). In animal study, sesame decreased total cholesterol, LDL cholesterol, VLDL cholesterol, triglycerides, with elevated HDL cholesterol levels under some conditions (182; 307; 308; 309; 310; 311; 312; 313; 314; 87) but not others (84; 87; 498; 499).
  • GlucoseGlucose: In patients with diabetes, sesame oil caused a decrease in plasma glucose (25; 26; 23; 13). In diabetic mice, an extract from defatted sesame seed had a hypoglycemic effect (295). In experimentally induced diabetic rats, sesame oil significantly reduced blood glucose levels (296; 297).
  • Plasma sodium levelsPlasma sodium levels: During sesame oil supplementation oil in place of other cooking oils in hypertensive diabetics, plasma sodium levels were reduced (25; 26; 24).
  • TaurineTaurine: Lysophosphatidylcholine isolated from a sesame seed extract inhibited the taurine uptake in human intestinal epithelial Caco-2 cells (599).

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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